Aplasys offers a number of mRNA engineering services. Starting from a simple evaluation of the coding sequence performance to a complete design of protein expression using our in-house computer-aided technology. All of our computational services are guaranteed by the quality assurance procedures executed within the wet lab environment.
- Identify the bottlenecks.
- Optimize the sequence performance.
- Estimate the protein yield.
- Optimize host conditions for maximum protein yield like mRNA competition, ribosome depletion, tRNA spectrum and series of other parameters.
- Identify best performing expression host by highly parallelized protein expression simulation.
- In-depth performance analysis of the protein expression process.
- Novel strategies for vector design for scale-up.
- Evaluation of initiation, termination and elongation rates as well as a large number of other factors.