WHAT IT DOES?
The virtual protein expression from Aplasys is designed to meet the need of wet lab professionals who only want to evaluate the performance of the coding sequence or who have any kind of difficulty achieving the desired protein yield. Through our solution offers a detailed study on how the complex interplay of the codon usage, mRNA translation initiation, amino acid elongation and translation termination influence the protein expression yield. We identify the bottlenecks within the protein formation process, in addition to optimizing the sequence and estimating the yield within the expression host or a cell-free system selected by the user.
This service offers fast turn-around time and the precise information on the best way to construct your coding sequence if you already know the expression environment. Aplasys uses computational solution that constantly undergoes wet lab validation and quality assurance to guarantee precise estimates of the protein yield. The user has to have an idea of the initial coding sequence for the target protein and the expression environment. This service answers two of the user’s questions “how my coding sequence will perform in my preferred environment and how to boost its performace”.